I am coming across an error that I have not seen described on any forum or discussion of Mi box known bugs. I bought a Mi Box 3 on Friday, watched a movie, it worked flawlessly, and then I updated it to Oreo. Now whenever I watch anything with 5.1 audio on Plex, the audio cuts out completely after one minute. I cannot find a solution to this, and I'm guessing the only thing that will fix it will be an update.
Edit: /u/cfoucher's solution of turning off automatically change quality did the trick. Setting it to a static video quality and audio to original appears to have fixed it
For me the issue was the Automatically Change Quality setting. Try turning that off.